MetI

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  • Description: O-succinylhomoserine lyase (L-cysteine, H2S, methanethiol, elimination)

Gene name metI
Synonyms yjcI
Essential no
Product O-succinylhomoserine lyase
(L-cysteine, H2S, methanethiol, elimination)
Function biosynthesis of methionine
Gene expression levels in SubtiExpress: metI
Metabolic function and regulation of this protein in SubtiPathways:
metI
MW, pI 41 kDa, 5.019
Gene length, protein length 1119 bp, 373 aa
Immediate neighbours yjcH, metC
Sequences Protein DNA DNA_with_flanks
Genetic context
YjcI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MetI expression.png




























Categories containing this gene/protein

biosynthesis/ acquisition of amino acids

This gene is a member of the following regulons

S-box

The gene

Basic information

  • Locus tag: BSU11870

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism: S-box: transcription termination/ antitermination, the S-box riboswitch binds S-adenosylmethionine resulting in termination PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References