DinB

• Description: nuclease inhibitor
  
  

Gene name	dinB
Synonyms
Essential	no
Product	nuclease inhibitor
Function	response to DNA damage
Gene expression levels in SubtiExpress: dinB
MW, pI	19 kDa, 5.614
Gene length, protein length	516 bp, 172 aa
Immediate neighbours	ydgF, ydgG
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

DNA repair/ recombination

This gene is a member of the following regulons

LexA regulon

The gene

Basic information

• Locus tag: BSU05630

Database entries

• BsubCyc: BSU05630

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: dinB family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU05630

• Structure:

• UniProt: Q02886

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: dinB PubMed

• Expression browser: dinB PubMed

• Sigma factor:

• Regulation:
  • induced by DNA damage (LexA) PubMed

• Regulatory mechanism:
  • LexA: transcription repression PubMed

• Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: