PbpC

• Description: penicillin-binding protein 3
  
  

Gene name	pbpC
Synonyms	ycsM, yzsA
Essential	no
Product	penicillin-binding protein 3
Function	unknown
Gene expression levels in SubtiExpress: pbpC
Interactions involving this protein in SubtInteract: PbpC
MW, pI	74 kDa, 6.202
Gene length, protein length	2004 bp, 668 aa
Immediate neighbours	yczJ, ycsN
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall synthesis

The gene

Basic information

• Locus tag: BSU04140

Database entries

• BsubCyc: BSU04140

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: transpeptidase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • may be part of the cell wall biosynthetic complex PubMed
  • folding requires PrsA PubMed

• Localization: cell membrane (according to Swiss-Prot), extracellular (signal peptide) PubMed

Database entries

• BsubCyc: BSU04140

• Structure:

• UniProt: P42971

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: pbpC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Jeff Errington lab

• Antibody: