YdeA

• Description: glyoxalase III-like enzyme
  
  

Gene name	ydeA
Synonyms
Essential	no
Product	glyoxalase III-like enzyme
Function	detoxification of methylglyoxal
Gene expression levels in SubtiExpress: ydeA
MW, pI	22 kDa, 5.644
Gene length, protein length	591 bp, 197 aa
Immediate neighbours	ydzN, cspC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

resistance against oxidative and electrophile stress

The gene

Basic information

• Locus tag: BSU05110

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • methylglyoxal --> D-lactate PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 3F5D

• UniProt: P96658

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ydeA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Pete Chandrangsu, Renata Dusi, Chris J Hamilton, John D Helmann
Methylglyoxal resistance in Bacillus subtilis: contributions of bacillithiol-dependent and independent pathways.
Mol Microbiol: 2014, 91(4);706-15
[PubMed:24330391] [WorldCat.org] [DOI] (I p)