PtpZ

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Gene name ptpZ
Synonyms ywqE
Essential no
Product phosphotyrosine protein phosphatase,
antagonist to PtkA
Function protein tyrosine dephosphorylation
Gene expression levels in SubtiExpress: ptpZ
Interactions involving this protein in SubtInteract: PtpZ
MW, pI 28 kDa, 6.66
Gene length, protein length 762 bp, 254 aa
Immediate neighbours ugd, ptkA
Sequences Protein DNA DNA_with_flanks
Genetic context
YwqE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PtpZ expression.png















Categories containing this gene/protein

biofilm formation, protein modification

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

  • Locus tag: BSU36240

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate (according to Swiss-Prot), dephosphorylation of Ugd, TuaD and PtkA PubMed
  • Protein family: cpsB/capC family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: *
    • GP1609 (spc), available in the Stülke lab
    • GP1610 (ptkA-ptpZ, spc), available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References