YbxA

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Gene name ybxA
Synonyms ybaD, ecfA1
Essential no
Product ECF transporter (ATP-binding protein)
Function uptake of micronutrients
Gene expression levels in SubtiExpress: ybxA
Interactions involving this protein in SubtInteract: YbxA
MW, pI 31 kDa, 4.766
Gene length, protein length 843 bp, 281 aa
Immediate neighbours rplQ, ybaE
Sequences Protein DNA DNA_with_flanks
Genetic context
YbxA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YbxA expression.png















Categories containing this gene/protein

ECF transporter, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU01450

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: EcfA transporter
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
    • 4HUQ (EcfA1-EcfA2-EcfT-FolT complex of Lactobacillus brevis), PubMed
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews


Original publications

Ke Xu, Minhua Zhang, Qin Zhao, Fang Yu, Hui Guo, Chengyuan Wang, Fangyuan He, Jianping Ding, Peng Zhang
Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis.
Nature: 2013, 497(7448);268-71
[PubMed:23584589] [WorldCat.org] [DOI] (I p)

Josy ter Beek, Ria H Duurkens, Guus B Erkens, Dirk Jan Slotboom
Quaternary structure and functional unit of energy coupling factor (ECF)-type transporters.
J Biol Chem: 2011, 286(7);5471-5
[PubMed:21135102] [WorldCat.org] [DOI] (I p)