DesR

• Description: two-component response regulator, regulation of cold shock expression of des
  
  

Gene name	desR
Synonyms	yocG
Essential	no
Product	two-component response regulator
Function	regulation of cold shock expression of des
Gene expression levels in SubtiExpress: desR
Interactions involving this protein in SubtInteract: DesR
Metabolic function and regulation of this protein in SubtiPathways: desR
MW, pI	22 kDa, 4.885
Gene length, protein length	597 bp, 199 aa
Immediate neighbours	desK, yocH
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

lipid metabolism/ other, transcription factors and their control, cold stress proteins, membrane proteins, phosphoproteins

The DesR regulon:

• des

The gene

Basic information

• Locus tag: BSU19200

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: transcription activation of the des operon when phosphorylated by DesK

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated by DesK on an Asp residue

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • DesK-DesR

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O34723

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: desK-desR PubMed

• Expression browser: desR PubMed

• Sigma factor:

• Regulation:
  • induced by cold shock (18-fold) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

• Diego de Mendoza, Universidad Nacional de Rosario, Argentine homepage