CotO

• Description: spore coat morphogenetic protein, controls assembly of the coat layers and coat surface topography
  
  

Gene name	cotO
Synonyms	yjbX
Essential	no
Product	spore coat morphogenetic protein
Function	controls assembly of the coat layers and coat surface topography
Gene expression levels in SubtiExpress: cotO
MW, pI	25 kDa, 6.376
Gene length, protein length	681 bp, 227 aa
Immediate neighbours	fabI, cotZ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU11730

Phenotypes of a mutant

spores are defective in germination PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:
  • outer spore coat, localization depends on CotE PubMed

Database entries

• Structure:

• UniProt: O31622

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cotO (according to DBTBS)

• Expression browser: cotO PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • repressed by casamino acids PubMed
  • expressed during sporulation in the mother cell PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: