ZnuC

• Description: ABC transporter for zinc (ATP-binding protein)
  
  

Gene name	znuC
Synonyms	ycdI
Essential	no
Product	ABC transporter for zinc (ATP-binding protein)
Function	zinc uptake
Gene expression levels in SubtiExpress: znuC
Interactions involving this protein in SubtInteract: ZnuC
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	26 kDa, 8.198
Gene length, protein length	693 bp, 231 aa
Immediate neighbours	znuA, znuB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), membrane proteins

This gene is a member of the following regulons

Zur regulon

The gene

Basic information

• Locus tag: BSU02860

Phenotypes of a mutant

• • reduced genetic competence, can be rescued by the addition of excess zinc PubMed
  • reduced expression of the comFA-comFB-comFC-yvyF-flgM-yvyG-flgK-flgL operon PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transporter domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: ZnuA-ZnuB-ZnuC PubMed

• Localization: associated to the membrane (via ZnuB) PubMed

Database entries

• Structure:

• UniProt: O34946

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: znuA-znuC-znuB PubMed

• Expression browser: znuC PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by zinc starvation (Zur) PubMed

• Regulatory mechanism:
  • Zur: transcription repression in the presence of zinc PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: