MutSB

• Description: probable DNA mismatch repair protein
  
  

Gene name	mutSB
Synonyms	yshD
Essential	no
Product	probable DNA mismatch repair protein
Function	DNA repair
Gene expression levels in SubtiExpress: mutSB
MW, pI	87 kDa, 5.79
Gene length, protein length	2355 bp, 785 aa
Immediate neighbours	yshE, polX
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

DNA repair/ recombination, membrane proteins

The gene

Basic information

• Locus tag: BSU28580

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: DNA mismatch repair mutS family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94545

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: mutSB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A845 ( mutSB::cat), PubMed, available at BGSC
  • 1A845 ( mutSB::cat), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Alessandra Albertini, University of Pavia, Italy homepage

References

Reviews

Justin S Lenhart, Jeremy W Schroeder, Brian W Walsh, Lyle A Simmons
DNA repair and genome maintenance in Bacillus subtilis.
Microbiol Mol Biol Rev: 2012, 76(3);530-64
[PubMed:22933559] [WorldCat.org] [DOI] (I p)