CspR

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  • Description: similar to tRNA (Um34/Cm34) methyltransferase

Gene name cspR
Synonyms ygaR
Essential yes PubMed
Product tRNA (Um34/Cm34) methyltransferase homolog
Function translation
Gene expression levels in SubtiExpress: cspR
MW, pI 18 kDa, 6.054
Gene length, protein length 480 bp, 160 aa
Immediate neighbours yhbB, yhbD
Sequences Protein DNA DNA_with_flanks
Genetic context
CspR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CspR expression.png















Categories containing this gene/protein

translation, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU08930

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • catalyzes the methyl transfer from S-adenosyl-L-methionine to tRNA(Leu)(CAA) and tRNA(Leu)(UAA) isoacceptors PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ru-Juan Liu, Mi Zhou, Zhi-Peng Fang, Meng Wang, Xiao-Long Zhou, En-Duo Wang
The tRNA recognition mechanism of the minimalist SPOUT methyltransferase, TrmL.
Nucleic Acids Res: 2013, 41(16);7828-42
[PubMed:23804755] [WorldCat.org] [DOI] (I p)