YrpC

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  • Description: glutamate racemase

Gene name yrpC
Synonyms
Essential no
Product glutamate racemase
Function peptidoglycan precursor biosynthesis
Gene expression levels in SubtiExpress: yrpC
Metabolic function and regulation of this protein in SubtiPathways:
Cell wall
MW, pI 29 kDa, 6.74
Gene length, protein length 795 bp, 265 aa
Immediate neighbours yrpB, yrpD
Sequences Protein DNA DNA_with_flanks
Genetic context
YrpC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YrpC expression.png




























Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU26810

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-glutamate = D-glutamate (according to Swiss-Prot)
  • Protein family: aspartate/glutamate racemases family (according to Swiss-Prot)
  • Paralogous protein(s): RacE

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 2JFN (from Escherichia coli, 36% identity, 54% similarity) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation: expressed only in minimal medium, not in complex medium PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Keitarou Kimura, Lam-Son Phan Tran, Yoshifumi Itoh
Roles and regulation of the glutamate racemase isogenes, racE and yrpC, in Bacillus subtilis.
Microbiology (Reading): 2004, 150(Pt 9);2911-2920
[PubMed:15347750] [WorldCat.org] [DOI] (P p)