YxdJ

• Description: two-component response regulator, regulation of the ABC transporter YxdL-YxdM in response to the cationic antimicrobial peptide, LL-37
  
  

Gene name	yxdJ
Synonyms
Essential	no
Product	two-component response regulator
Function	resistance against toxic peptides
Gene expression levels in SubtiExpress: yxdJ
Interactions involving this protein in SubtInteract: YxdJ
MW, pI	26 kDa, 4.937
Gene length, protein length	687 bp, 229 aa
Immediate neighbours	yxdK, iolJ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, resistance against toxins/ antibiotics, phosphoproteins

The YxdJ regulon:

• yxdL-yxdM-yxeA

The gene

Basic information

• Locus tag: BSU39660

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated by YxdK on an Asp residue

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YxdK-YxdJ

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P42421

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yxdJ-yxdK PubMed

• Expression browser: yxdJ PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: