YrvO

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  • Description: cysteine desulfurase involved in tRNA thiolation

Gene name yrvO
Synonyms nifS, iscS
Essential yes PubMed
Product cysteine desulfurase
Function tRNA modification
Gene expression levels in SubtiExpress: yrvO
MW, pI 41 kDa, 5.463
Gene length, protein length 1137 bp, 379 aa
Immediate neighbours trmU, cymR
Gene sequence (+200bp) Protein sequence
Genetic context
YrvO context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YrvO expression.png
























Categories containing this gene/protein

essential genes, translation, phosphoproteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU27510

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • phosphorylated on Arg-385 PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1EG5 (from Thermotoga maritima, 37% identity, 54% similarity) PubMed
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References