YqcF

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  • Description: antitoxin

Gene name yqcF
Synonyms
Essential no
Product antitoxin
Function inhibition of the cytotoxic activity of YqcG
Gene expression levels in SubtiExpress: yqcF
Interactions involving this protein in SubtInteract: YqcF
MW, pI 21 kDa, 4.268
Gene length, protein length 576 bp, 192 aa
Immediate neighbours yqcG, yqxJ
Sequences Protein DNA DNA_with_flanks
Genetic context
YqcF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YqcF expression.png
























Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, Skin element

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU25870

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Laura E Holberger, Fernando Garza-Sánchez, James Lamoureux, David A Low, Christopher S Hayes
A novel family of toxin/antitoxin proteins in Bacillus species.
FEBS Lett: 2012, 586(2);132-6
[PubMed:22200572] [WorldCat.org] [DOI] (I p)

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)