YotD

• Description: similar to acyl-CoA synthetase
  
  

Gene name	yotD
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yotD
MW, pI	4 kDa, 3.816
Gene length, protein length	129 bp, 43 aa
Immediate neighbours	yotE, yotC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

SP-beta prophage, poorly characterized/ putative enzymes

This gene is a member of the following regulons

CsoR regulon

The gene

Basic information

• Locus tag: BSU19920

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s): contains an iron-sulfur cluster

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34407

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yotD PubMed

• Sigma factor:

• Regulation:
  • 11-fold induced by copper stress (CsoR) PubMed

• Regulatory mechanism:
  • CsoR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Shashi Chillappagari, Andreas Seubert, Hein Trip, Oscar P Kuipers, Mohamed A Marahiel, Marcus Miethke
Copper stress affects iron homeostasis by destabilizing iron-sulfur cluster formation in Bacillus subtilis.
J Bacteriol: 2010, 192(10);2512-24
[PubMed:20233928] [WorldCat.org] [DOI] (I p)

Valentina Tosato, Alessandra M Albertini, Michela Zotti, Sabrina Sonda, Carlo V Bruschi
Sequence completion, identification and definition of the fengycin operon in Bacillus subtilis 168.
Microbiology (Reading): 1997, 143 ( Pt 11);3443-3450
[PubMed:9387222] [WorldCat.org] [DOI] (P p)