NdoAI

Gene name	ndoAI
Synonyms	ydcD
Essential	no
Product	antitoxin
Function	inhibition of NdoA
Gene expression levels in SubtiExpress: ndoAI
Interactions involving this protein in SubtInteract: NdoAI
MW, pI	10 kDa, 6.138
Gene length, protein length	279 bp, 93 aa
Immediate neighbours	alr, ndoA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins

The gene

Basic information

• Locus tag: BSU04650

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: mazE/ndoAI family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • NdoAI-EndoA PubMed

• Localization:

Database entries

• Structure:

• UniProt: P96621

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ndoAI-ndoA PubMed

• Expression browser: ndoAI PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Shivangi Agarwal, Shivani Agarwal, Rakesh Bhatnagar
Identification and characterization of a novel toxin-antitoxin module from Bacillus anthracis.
FEBS Lett: 2007, 581(9);1727-34
[PubMed:17416361] [WorldCat.org] [DOI] (P p)

Olivier Pellegrini, Nathalie Mathy, Arhonda Gogos, Lawrence Shapiro, Ciarán Condon
The Bacillus subtilis ydcDE operon encodes an endoribonuclease of the MazF/PemK family and its inhibitor.
Mol Microbiol: 2005, 56(5);1139-48
[PubMed:15882409] [WorldCat.org] [DOI] (P p)