CwlK

• Description: peptidoglycan hydrolytic L,D-endopeptidase
  
  

Gene name	cwlK
Synonyms	ycdD
Essential	no
Product	peptidoglycan hydrolytic L,D-endopeptidase
Function	cell wall turnover
Gene expression levels in SubtiExpress: cwlK
MW, pI	18 kDa, 5.66
Gene length, protein length	501 bp, 167 aa
Immediate neighbours	ycdC, rapJ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall degradation/ turnover, membrane proteins

The gene

Basic information

• Locus tag: BSU02810

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: peptidase M15C family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane PubMed

Database entries

• Structure:

• UniProt: O34360

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: cwlK PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Ciaran Condon, IBPC, Paris, France Homepage

References

Tatsuya Fukushima, Yang Yao, Toshihiko Kitajima, Hiroki Yamamoto, Junichi Sekiguchi
Characterization of new L,D-endopeptidase gene product CwlK (previous YcdD) that hydrolyzes peptidoglycan in Bacillus subtilis.
Mol Genet Genomics: 2007, 278(4);371-83
[PubMed:17588176] [WorldCat.org] [DOI] (P p)