PstS

• Description: phosphate ABC transporter (binding protein)
  
  

Gene name	pstS
Synonyms	yqgG, yzmB
Essential	no
Product	phosphate ABC transporter (binding protein)
Function	high-affinity phosphate uptake
Gene expression levels in SubtiExpress: pstS
Interactions involving this protein in SubtInteract: PstS
MW, pI	31 kDa, 4.845
Gene length, protein length	900 bp, 300 aa
Immediate neighbours	pstC, pbpA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, phosphate metabolism, membrane proteins, phosphoproteins

This gene is a member of the following regulons

PhoP regulon

The gene

Basic information

• Locus tag: BSU24990

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: pstS family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated on ser/ thr/ tyr PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • (PstBA-PstBB)-(PstA-PstC)-PstS PubMed

• Localization:
  • cell membrane (according to Swiss-Prot)
  • extracellular (signal peptide) PubMed

Database entries

• Structure:

• UniProt: P46338

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: pstS-pstC-pstA-pstBA-pstBB PubMed

• Expression browser: pstS PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • expressed under conditions of phosphate limitation (5000-fold induced) (PhoP) PubMed

• Regulatory mechanism:
  • PhoP: transcription activation PubMed

• Additional information:
  • mRNA processing between pstS and pstC to maintain higher concentrations of PstS relative to other components of the ABC transporter PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Marion Hulett, University of Illinois at Chicago, USA Homepage