AdaA

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  • Description: trigger enzyme: methylphosphotriester-DNA alkyltransferase/ transcriptional activator of the adaA-adaB operon

Gene name adaA
Synonyms
Essential no
Product trigger enzyme: methylphosphotriester-DNA alkyltransferase/
transcriptional activator of the adaAB operon
Function adaptive response to alkylative DNA damage
Gene expression levels in SubtiExpress: adaA
MW, pI 24 kDa, 9.185
Gene length, protein length 633 bp, 211 aa
Immediate neighbours alkA, adaB
Sequences Protein DNA DNA_with_flanks
Genetic context
AdaA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AdaA expression.png
























Categories containing this gene/protein

DNA repair/ recombination, transcription factors and their control, trigger enzyme

This gene is a member of the following regulons

AdaA regulon

The gene

Basic information

  • Locus tag: BSU01810

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

F Morohoshi, K Hayashi, N Munkata
Bacillus subtilis alkA gene encoding inducible 3-methyladenine DNA glycosylase is adjacent to the ada operon.
J Bacteriol: 1993, 175(18);6010-7
[PubMed:8376346] [WorldCat.org] [DOI] (P p)

F Morohoshi, K Hayashi, N Munakata
Bacillus subtilis ada operon encodes two DNA alkyltransferases.
Nucleic Acids Res: 1990, 18(18);5473-80
[PubMed:2120677] [WorldCat.org] [DOI] (P p)