YacO

From SubtiWiki
Revision as of 09:14, 14 May 2013 by 134.76.70.252 (talk)
Jump to: navigation, search
  • Description: putative 23S rRNA methyltransferase

Gene name yacO
Synonyms
Essential no
Product putative 23S rRNA methyltransferase
Function unknown
Gene expression levels in SubtiExpress: yacO
Metabolic function and regulation of this protein in SubtiPathways:
tRNA charging
MW, pI 27 kDa, 8.633
Gene length, protein length 747 bp, 249 aa
Immediate neighbours mrnC, yacP
Sequences Protein DNA DNA_with_flanks
Genetic context
YacO context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YacO expression.png




























Categories containing this gene/protein

translation

This gene is a member of the following regulons

T-box

The gene

Basic information

  • Locus tag: BSU00960

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: RNA methyltransferase trmH family (according to Swiss-Prot)
  • Paralogous protein(s): YsgA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism: T-box, overlaps a transcription terminator upstream of cysE: transcription antitermination PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ana Gutiérrez-Preciado, Tina M Henkin, Frank J Grundy, Charles Yanofsky, Enrique Merino
Biochemical features and functional implications of the RNA-based T-box regulatory mechanism.
Microbiol Mol Biol Rev: 2009, 73(1);36-61
[PubMed:19258532] [WorldCat.org] [DOI] (I p)