PbuX

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  • Description: xanthine transport in/out via proton symport

Gene name pbuX
Synonyms ypaQ
Essential no
Product xanthine permease
Function xanthine uptake
Gene expression levels in SubtiExpress: pbuX
Metabolic function and regulation of this protein in SubtiPathways:
Purine salvage, Nucleotides (regulation)
MW, pI 46 kDa, 8.793
Gene length, protein length 1314 bp, 438 aa
Immediate neighbours bcsA, xpt
Sequences Protein DNA Advanced_DNA
Genetic context
PbuX context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PbuX expression.png




























Categories containing this gene/protein

transporters/ other, biosynthesis/ acquisition of nucleotides, membrane proteins

This gene is a member of the following regulons

G-box, PurR regulon

The gene

Basic information

  • Locus tag: BSU22060

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of adenine or adenosine (PurR) PubMed
    • induced in the absence of guanine (G-box) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References