PbuX

• Description: xanthine transport in/out via proton symport
  
  

Gene name	pbuX
Synonyms	ypaQ
Essential	no
Product	xanthine permease
Function	xanthine uptake
Gene expression levels in SubtiExpress: pbuX
Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Nucleotides (regulation)
MW, pI	46 kDa, 8.793
Gene length, protein length	1314 bp, 438 aa
Immediate neighbours	bcsA, xpt
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, biosynthesis/ acquisition of nucleotides, membrane proteins

This gene is a member of the following regulons

G-box, PurR regulon

The gene

Basic information

• Locus tag: BSU22060

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: membrane PubMed

Database entries

• Structure:

• UniProt: P42086

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: xpt-pbuX PubMed

• Expression browser: pbuX PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed in the presence of adenine or adenosine (PurR) PubMed
  • induced in the absence of guanine (G-box) PubMed

• Regulatory mechanism:
  • G-box: transcription termination/ antitermination (riboswitch) PubMed
  • PurR: transcription repression (molecular inducer: PRPP) PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: