KamA

• Description: lysine 2,3-aminomutase
  
  

Gene name	kamA
Synonyms	yodO
Essential	no
Product	lysine 2,3-aminomutase
Function	unknown
Gene expression levels in SubtiExpress: kamA
MW, pI	53 kDa, 6.04
Gene length, protein length	1413 bp, 471 aa
Immediate neighbours	yokU, yodP
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins, poorly characterized/ putative enzymes

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU19690

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: L-lysine = beta-lysine

• Protein family: UPF0720 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34676

• KEGG entry: [2]

• E.C. number: 5.4.3.2

Expression and regulation

• Operon: yodT-yodS-yodR-yodQ-yodP-kamA-yokU PubMed

• Expression browser: kamA PubMed

• Sigma factor: SigE PubMed

• Regulation: expressed early during sporuation in the mother cell (SigE) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Andrea Feucht, Louise Evans, Jeff Errington
Identification of sporulation genes by genome-wide analysis of the sigmaE regulon of Bacillus subtilis.
Microbiology (Reading): 2003, 149(Pt 10);3023-3034
[PubMed:14523133] [WorldCat.org] [DOI] (P p)

D Chen, F J Ruzicka, P A Frey
A novel lysine 2,3-aminomutase encoded by the yodO gene of bacillus subtilis: characterization and the observation of organic radical intermediates.
Biochem J: 2000, 348 Pt 3(Pt 3);539-49
[PubMed:10839984] [WorldCat.org] (P p)