NprB

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  • Description: extracellular neutral protease B

Gene name nprB
Synonyms
Essential no
Product extracellular neutral protease B
Function degradation of proteins
Gene expression levels in SubtiExpress: nprB
MW, pI 59 kDa, 5.322
Gene length, protein length 1614 bp, 538 aa
Immediate neighbours yitR, yitS
Sequences Protein DNA Advanced_DNA
Genetic context
NprB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NprB expression.png















Categories containing this gene/protein

utilization of nitrogen sources other than amino acids, proteolysis

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU11100

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Similar, but not identical, to that of thermolysin (according to Swiss-Prot)
  • Protein family: peptidase M4 family (according to Swiss-Prot)
  • Paralogous protein(s): NprE

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications