NhaX

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  • Description: general stress protein, putative regulator of nhaC

Gene name nhaX
Synonyms yheK
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: nhaX
MW, pI 17 kDa, 4.438
Gene length, protein length 498 bp, 166 aa
Immediate neighbours nhaC, yheJ
Sequences Protein DNA Advanced_DNA
Genetic context
NhaX context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NhaX expression.png















Categories containing this gene/protein

general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU09690

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: universal stress protein A family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: nhaX (according to DBTBS)
  • Regulation:
    • induced by stress (SigB) PubMed
    • strongly induced in response to glucose starvation in M9 medium PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224] [WorldCat.org] [DOI] (P p)

Z Prágai, C Eschevins, S Bron, C R Harwood
Bacillus subtilis NhaC, an Na+/H+ antiporter, influences expression of the phoPR operon and production of alkaline phosphatases.
J Bacteriol: 2001, 183(8);2505-15
[PubMed:11274110] [WorldCat.org] [DOI] (P p)