RsbU
- Description: protein serine phosphatase, environmental PP2C, dephosphorylates RsbV
| Gene name | rsbU |
| Synonyms | |
| Essential | no |
| Product | protein serine phosphatase, environmental PP2C |
| Function | control of SigB activity |
| Gene expression levels in SubtiExpress: rsbU | |
| Interactions involving this protein in SubtInteract: RsbU | |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 38 kDa, 4.906 |
| Gene length, protein length | 1005 bp, 335 aa |
| Immediate neighbours | rsbT, rsbV |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
protein modification, sigma factors and their control
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04700
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: O-phospho-L(or D)-serine + H2O = L(or D)-serine + phosphate (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 2J6Y
- UniProt: P40399
- KEGG entry: [3]
- E.C. number: 3.1.3.3
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Bill Haldenwang, San Antonio, USA
- Chet Price, Davis, USA homepage
- Rick Lewis, Newcastle, UK homepage
Your additional remarks
References
Reviews
Jon Marles-Wright, Richard J Lewis
The stressosome: molecular architecture of a signalling hub.
Biochem Soc Trans: 2010, 38(4);928-33
[PubMed:20658979]
[WorldCat.org]
[DOI]
(I p)
Original publications
Additional publications: PubMed
