YkrK

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  • Description: transcription repressor of htpX expression

Gene name ykrK
Synonyms
Essential no
Product transcription repressor of htpX
Function regulation of membrane protein quality control
Gene expression levels in SubtiExpress: ykrK
MW, pI 26 kDa, 6.153
Gene length, protein length 699 bp, 233 aa
Immediate neighbours sspD, htpX
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YkrK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YkrK expression.png















Categories containing this gene/protein

Transcription factors and their control

This gene is a member of the following regulons

The YkrK regulon: htpX

The gene

Basic information

  • Locus tag: BSU13480

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
    • might be subject to autoregulation PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ta-Hui Lin, Shih-Chien Huang, Gwo-Chyuan Shaw
Reexamining transcriptional regulation of the Bacillus subtilis htpX gene and the ykrK gene, encoding a novel type of transcriptional regulator, and redefining the YkrK operator.
J Bacteriol: 2012, 194(24);6758-65
[PubMed:23042994] [WorldCat.org] [DOI] (I p)

Bogumila C Marciniak, Hein Trip, Fabrizia Fusetti, Oscar P Kuipers
Regulation of ykrL (htpX) by Rok and YkrK, a novel type of regulator in Bacillus subtilis.
J Bacteriol: 2012, 194(11);2837-45
[PubMed:22447908] [WorldCat.org] [DOI] (I p)