YydG

• Description: oxidoreductase, modification of YydF
  
  

Gene name	yydG
Synonyms
Essential	no
Product	oxidoreductase
Function	control of LiaR-LiaS activity
Gene expression levels in SubtiExpress: yydG
Interactions involving this protein in SubtInteract: YydG
MW, pI	37 kDa, 5.865
Gene length, protein length	957 bp, 319 aa
Immediate neighbours	yydH, yydF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

• Locus tag: BSU40170

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YydF-YydG PubMed

• Localization:

Database entries

• Structure:

• UniProt: Q45595

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yydF-yydG-yydH-yydI-yydJ PubMed

• Expression browser: yydG PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed by glucose (5-fold) PubMed
  • activated after transition to stationary phase(AbrB) PubMed

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:
  • the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Susanne Gebhard
ABC transporters of antimicrobial peptides in Firmicutes bacteria - phylogeny, function and regulation.
Mol Microbiol: 2012, 86(6);1295-317
[PubMed:23106164] [WorldCat.org] [DOI] (I p)

Original publications

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947

Bronwyn G Butcher, Yi-Pin Lin, John D Helmann
The yydFGHIJ operon of Bacillus subtilis encodes a peptide that induces the LiaRS two-component system.
J Bacteriol: 2007, 189(23);8616-25
[PubMed:17921301] [WorldCat.org] [DOI] (I p)

Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135] [WorldCat.org] [DOI] (P p)