YdaE

• Description: lyxose isomerase, general stress protein, survival of ethanol stress and low temperatures
  
  

Gene name	ydaE
Synonyms
Essential	no
Product	lyxose isomerase
Function	survival of ethanol stress and low temperatures
Gene expression levels in SubtiExpress: ydaE
MW, pI	19 kDa, 4.878
Gene length, protein length	501 bp, 167 aa
Immediate neighbours	ydaD, ydaF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB), Utilization of specific carbon sources

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU04200

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: D-lyxose = D-xylulose (according to Swiss-Prot)

• Protein family: D-lyxose ketol-isomerase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2Y0O PubMed

• UniProt: P96578

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ydaD-ydaE-ydaF-ydaG PubMed

• Expression browser: ydaE PubMed

• Sigma factor: SigB PubMed

• Regulation:
  • induced by stress (SigB) PubMed
  • strongly induced in response to glucose starvation in M9 medium PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

Anja Petersohn, Haike Antelmann, Ulf Gerth, Michael Hecker
Identification and transcriptional analysis of new members of the sigmaB regulon in Bacillus subtilis.
Microbiology (Reading): 1999, 145 ( Pt 4);869-880
[PubMed:10220166] [WorldCat.org] [DOI] (P p)