GerPF

• Description: spore germination protein, facilitates access of nutrient germinants to their cognate germinant receptors in spores’ inner membrane
  
  

Gene name	gerPF
Synonyms	yisC
Essential	no
Product	unknown
Function	germination
Gene expression levels in SubtiExpress: gerPF
MW, pI	7 kDa, 3.621
Gene length, protein length	225 bp, 75 aa
Immediate neighbours	hlpB, gerPE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

germination

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

• Locus tag: BSU10670

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: gerPA/gerPF family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O06716

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gerPA-gerPB-gerPC-gerPD-gerPE-gerPF (according to DBTBS)

• Expression browser: gerPF PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed during sporulation in the mother cell (SigK) PubMed
  • subject to negative regulation by GerE PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

J Behravan, H Chirakkal, A Masson, A Moir
Mutations in the gerP locus of Bacillus subtilis and Bacillus cereus affect access of germinants to their targets in spores.
J Bacteriol: 2000, 182(7);1987-94
[PubMed:10715007] [WorldCat.org] [DOI] (P p)