YloN

• Description: similar to rRNA adenosine methyltransferase for modification of 23S rRNA
  
  

Gene name	yloN
Synonyms
Essential	no
Product	rRNA methyltransferase
Function	rRNA modification
Gene expression levels in SubtiExpress: yloN
MW, pI	41 kDa, 6.788
Gene length, protein length	1089 bp, 363 aa
Immediate neighbours	yloM, prpC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation

The gene

Basic information

• Locus tag: BSU15750

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: RlmN family (according to Swiss-Prot), SAM enzyme superfamily

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O34617

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yloN PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A819 ( yloN::erm), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Perry A Frey, Adrian D Hegeman, Frank J Ruzicka
The Radical SAM Superfamily.
Crit Rev Biochem Mol Biol: 2008, 43(1);63-88
[PubMed:18307109] [WorldCat.org] [DOI] (I p)

Seok-Ming Toh, Liqun Xiong, Taeok Bae, Alexander S Mankin
The methyltransferase YfgB/RlmN is responsible for modification of adenosine 2503 in 23S rRNA.
RNA: 2008, 14(1);98-106
[PubMed:18025251] [WorldCat.org] [DOI] (I p)