YxkO

• Description: ADP/ATP-dependent NAD(P)H-hydrate dehydratase, general stress protein, survival of ethanol stress
  
  

Gene name	yxkO
Synonyms
Essential	no
Product	ADP/ATP-dependent NAD(P)H-hydrate dehydratase
Function	survival of ethanol stress
Gene expression levels in SubtiExpress: yxkO
MW, pI	29 kDa, 5.488
Gene length, protein length	828 bp, 276 aa
Immediate neighbours	yxlA, cydD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU38720

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1KYH

• UniProt: P94368

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yxkO PubMed

• Expression browser: yxkO PubMed

• Sigma factor: SigB PubMed

• Regulation:
  • induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Igor A Shumilin, Marcin Cymborowski, Olga Chertihin, Kula N Jha, John C Herr, Scott A Lesley, Andrzej Joachimiak, Wladek Minor
Identification of unknown protein function using metabolite cocktail screening.
Structure: 2012, 20(10);1715-25
[PubMed:22940582] [WorldCat.org] [DOI] (I p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

R-g Zhang, J Grembecka, E Vinokour, F Collart, I Dementieva, W Minor, A Joachimiak
Structure of Bacillus subtilis YXKO--a member of the UPF0031 family and a putative kinase.
J Struct Biol: 2002, 139(3);161-70
[PubMed:12457846] [WorldCat.org] [DOI] (P p)

Ken-Ichi Yoshida, Izumi Ishio, Eishi Nagakawa, Yoshiyuki Yamamoto, Mami Yamamoto, Yasutaro Fujita
Systematic study of gene expression and transcription organization in the gntZ-ywaA region of the Bacillus subtilis genome.
Microbiology (Reading): 2000, 146 ( Pt 3);573-579
[PubMed:10746760] [WorldCat.org] [DOI] (P p)