YdaP

• Description: general stress protein, required for survival of ethanol stress, similar to actolactate synthase

Gene name	ydaP
Synonyms
Essential	no
Product	putative pyruvate oxidase
Function	unknown
Gene expression levels in SubtiExpress: ydaP
MW, pI	62 kDa, 5.217
Gene length, protein length	1722 bp, 574 aa
Immediate neighbours	mutT, ydzK
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB), poorly characterized/ putative enzymes

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU04340

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): AlsS, IlvB

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P96591

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ydaP PubMed

• Expression browser: ydaP PubMed

• Sigma factor: SigB PubMed

• Regulation: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: GP457 (spc), available in Stülke lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

Anja Petersohn, Haike Antelmann, Ulf Gerth, Michael Hecker
Identification and transcriptional analysis of new members of the sigmaB regulon in Bacillus subtilis.
Microbiology (Reading): 1999, 145 ( Pt 4);869-880
[PubMed:10220166] [WorldCat.org] [DOI] (P p)