PepF

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  • Description: oligoendopeptidase, inhibits sporulation upon overexpression

Gene name pepF
Synonyms yjbG
Essential no
Product oligoendopeptidase
Function protein degradation
Gene expression levels in SubtiExpress: pepF
MW, pI 69 kDa, 5.131
Gene length, protein length 1827 bp, 609 aa
Immediate neighbours coiA, yjbH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YjbG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PepF expression.png
























Categories containing this gene/protein

phosphorelay

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU11540

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase M3B family (according to Swiss-Prot)
  • Paralogous protein(s): YusX

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Kyoko Kanamaru, Sophie Stephenson, Marta Perego
Overexpression of the PepF oligopeptidase inhibits sporulation initiation in Bacillus subtilis.
J Bacteriol: 2002, 184(1);43-50
[PubMed:11741842] [WorldCat.org] [DOI] (P p)