YumB

• Description: unknown
  
  

Gene name	yumB
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yumB
MW, pI	44 kDa, 6.616
Gene length, protein length	1218 bp, 406 aa
Immediate neighbours	yuiA, yumC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

proteins of unknown function

The gene

Basic information

• Locus tag: BSU32100

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O05267

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yumB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

The gene is annotated in KEGG as an ortholog of NADH dehydrogenase EC 1.6.99.3. No EC annotation is available in Swiss-Prot. In MetaCyc it is marked as “similar to NADH dehydrogenase”. In the paper by Gyan et al. PubMed, the authors tested the growth of three B. subtilis genes potentially responsible for EC 1.6.99.3 (yumB, yjlD, and yutJ). Only yjlD- mutant showed a growth defect on the LB media, while the other two grew as well as wild type. PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Tzu-Lin Hsiao, Olga Revelles, Lifeng Chen, Uwe Sauer, Dennis Vitkup
Automatic policing of biochemical annotations using genomic correlations.
Nat Chem Biol: 2010, 6(1);34-40
[PubMed:19935659] [WorldCat.org] [DOI] (I p)

Smita Gyan, Yoshihiko Shiohira, Ichiro Sato, Michio Takeuchi, Tsutomu Sato
Regulatory loop between redox sensing of the NADH/NAD(+) ratio by Rex (YdiH) and oxidation of NADH by NADH dehydrogenase Ndh in Bacillus subtilis.
J Bacteriol: 2006, 188(20);7062-71
[PubMed:17015645] [WorldCat.org] [DOI] (P p)