CotI

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  • Description: spore coat protein

Gene name cotI
Synonyms ytaA
Essential no
Product spore coat protein
Function spore envelope
Gene expression levels in SubtiExpress: cotI
MW, pI 41 kDa, 4.989
Gene length, protein length 1071 bp, 357 aa
Immediate neighbours cotSA, ytaB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YtaA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
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Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

  • Locus tag: BSU30920

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: cotS family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Eric D Scheeff, Herbert L Axelrod, Mitchell D Miller, Hsiu-Ju Chiu, Ashley M Deacon, Ian A Wilson, Gerard Manning
Genomics, evolution, and crystal structure of a new family of bacterial spore kinases.
Proteins: 2010, 78(6);1470-82
[PubMed:20077512] [WorldCat.org] [DOI] (I p)

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

Erh-Min Lai, Nikhil D Phadke, Maureen T Kachman, Rebecca Giorno, Santiago Vazquez, Jenny A Vazquez, Janine R Maddock, Adam Driks
Proteomic analysis of the spore coats of Bacillus subtilis and Bacillus anthracis.
J Bacteriol: 2003, 185(4);1443-54
[PubMed:12562816] [WorldCat.org] [DOI] (P p)

Ritsuko Kuwana, Yasuhiro Kasahara, Machiko Fujibayashi, Hiromu Takamatsu, Naotake Ogasawara, Kazuhito Watabe
Proteomics characterization of novel spore proteins of Bacillus subtilis.
Microbiology (Reading): 2002, 148(Pt 12);3971-3982
[PubMed:12480901] [WorldCat.org] [DOI] (P p)