LytT

• Description: two-component response regulator, regulation of the rate of autolysis
  
  

Gene name	lytT
Synonyms
Essential	no
Product	two-component response regulator
Function	regulation of the rate of autolysis
Gene expression levels in SubtiExpress: lytT
Interactions involving this protein in SubtInteract: LytT
MW, pI	27 kDa, 5.081
Gene length, protein length	723 bp, 241 aa
Immediate neighbours	ysbA, lytS
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed 500px

Categories containing this gene/protein

cell wall degradation/ turnover, transcription factors and their control, membrane proteins, phosphoproteins

The gene

Basic information

• Locus tag: BSU28920

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated on Asp by LytS

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • LytT-LytS

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94514

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: lytT PubMed

• Expression browser: lytT PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)

A Wipat, N Carter, S C Brignell, B J Guy, K Piper, J Sanders, P T Emmerson, C R Harwood
The dnaB-pheA (256 degrees-240 degrees) region of the Bacillus subtilis chromosome containing genes responsible for stress responses, the utilization of plant cell walls and primary metabolism.
Microbiology (Reading): 1996, 142 ( Pt 11);3067-78
[PubMed:8969504] [WorldCat.org] [DOI] (P p)