YrvJ

• Description: similar to N-acetylmuramoyl-L-alanine amidase
  
  

Gene name	yrvJ
Synonyms
Essential	no
Product	peptidoglycan hydrolase
Function	cell wall metabolism
Gene expression levels in SubtiExpress: yrvJ
MW, pI	55 kDa, 5.192
Gene length, protein length	1554 bp, 518 aa
Immediate neighbours	yrzK, yrvI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall/ other

The gene

Basic information

• Locus tag: BSU27580

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot)

• Protein family: N-acetylmuramoyl-L-alanine amidase 3 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: contains an amidase_3 domain (like CwlC, CwlD, LytC, YqiI)

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O32041

• KEGG entry: [3]

• E.C. number: 3.5.1.28

Expression and regulation

• Operon: yrvJ PubMed

• Expression browser: yrvJ PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

T M Wendrich, M A Marahiel
Cloning and characterization of a relA/spoT homologue from Bacillus subtilis.
Mol Microbiol: 1997, 26(1);65-79
[PubMed:9383190] [WorldCat.org] [DOI] (P p)