NicK

Gene name	nicK
Synonyms	ydcR
Essential	no
Product	DNA relaxase, similar to transposon protein
Function	conjugation of ICE BS1
Gene expression levels in SubtiExpress: nicK
MW, pI	40 kDa, 5.131
Gene length, protein length	1056 bp, 352 aa
Immediate neighbours	ydcQ , ydcS
Gene sequence (+200bp)	Protein sequence
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

mobile genetic elements

The gene

Basic information

• Locus tag: BSU04870

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: plasmid replication initiation factor family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P96635

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: nicK PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Elisabeth Grohmann
Autonomous plasmid-like replication of Bacillus ICEBs1: a general feature of integrative conjugative elements?
Mol Microbiol: 2010, 75(2);261-3
[PubMed:19943906] [WorldCat.org] [DOI] (I p)

Original Publications

Catherine A Lee, Ana Babic, Alan D Grossman
Autonomous plasmid-like replication of a conjugative transposon.
Mol Microbiol: 2010, 75(2);268-79
[PubMed:19943900] [WorldCat.org] [DOI] (I p)

Catherine A Lee, Alan D Grossman
Identification of the origin of transfer (oriT) and DNA relaxase required for conjugation of the integrative and conjugative element ICEBs1 of Bacillus subtilis.
J Bacteriol: 2007, 189(20);7254-61
[PubMed:17693500] [WorldCat.org] [DOI] (P p)