DapI

• Description: N-acetyl-diaminopimelate deacetylase
  
  

Gene name	ykuR
Synonyms	dapL
Essential	yes PubMed
Product	N-acetyl-diaminopimelate deacetylase
Function	biosynthesis of lysine and peptidoglycan
Gene expression levels in SubtiExpress: ykuR
Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr
MW, pI	41 kDa, 5.102
Gene length, protein length	1122 bp, 374 aa
Immediate neighbours	ykuQ, ykuS
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, essential genes

The gene

Basic information

• Locus tag: BSU14190

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: N-acetyl-LL-2,6-diaminoheptanedioate + H₂O = acetate + LL-2,6-diaminoheptanedioate (according to Swiss-Prot)

• Protein family: peptidase M20A family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34916

• KEGG entry: [2]

• E.C. number: 3.5.1.47

Expression and regulation

• Operon:

• Expression browser: ykuR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

The gene is annotated in KEGG as an ortholog of N-acetyldiaminopimelate deacetylase EC 3.5.1.47. In MetaCyc it is marked as “similar to hippurate hydrolase”. No EC annotation is available in Swiss-Prot. No literature/experimental evidence supporting the annotation is available. PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: