ComZ

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Gene name comZ
Synonyms yjzA
Essential no
Product unknown
Function compentence
Gene expression levels in SubtiExpress: comZ
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 7 kDa, 4.37
Gene length, protein length 189 bp, 63 aa
Immediate neighbours med, yjzB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ComZ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComZ expression.png
























Categories containing this gene/protein

genetic competence

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU11310

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)

M Ogura, T Tanaka
Bacillus subtilis comZ (yjzA) negatively affects expression of comG but not comK.
J Bacteriol: 2000, 182(17);4992-4
[PubMed:10940045] [WorldCat.org] [DOI] (P p)

M Ogura, Y Ohshiro, S Hirao, T Tanaka
A new Bacillus subtilis gene, med, encodes a positive regulator of comK.
J Bacteriol: 1997, 179(20);6244-53
[PubMed:9335269] [WorldCat.org] [DOI] (P p)