OpuE

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Gene name opuE
Synonyms yerK
Essential no
Product proline transporter
Function compatible solute transport
Gene expression levels in SubtiExpress: opuE
Metabolic function and regulation of this protein in SubtiPathways:
Pro, Stress
MW, pI 53 kDa, 9.815
Gene length, protein length 1476 bp, 492 aa
Immediate neighbours sapB, gatC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
OpuE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
OpuE expression.png




























Categories containing this gene/protein

general stress proteins (controlled by SigB), transporters/ other, coping with hyper-osmotic stress, membrane proteins

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU06660

Phenotypes of a mutant

  • strong growth disadvantage in high-salinity minimal media lacking proline PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: solute symporter family
  • Paralogous protein(s): PutP

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulatory mechanism:
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Erhard Bremer, University of Marburg, Germany homepage

Your additional remarks

References