RNases
RNases are involved in the processing and degradation of the different classes of mRNAs, tRNAs, rRNAs and small RNAs
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Contents
Exoribonucleases
- RNase J1: 5'-3' activity
- RNase PH: 3'-5' activity
- YhaM: 3'-5' activity
- RNase R: 3'-5' activity
- polynucleotide phosphorylase: 3'-5' activity
- nano-RNase A: degrades oligonucleotides
- nano-RNase B: degrades oligonucleotides
Endoribonucleases
- RNase HII: cleaves RNA in RNA-DNA hybrids
- RNase HIII: cleaves RNA in RNA-DNA hybrids
- RNase Bsn: extracellular RNase
Unknown activity
Labs working on RNases
Key original publications
G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008]
[WorldCat.org]
[DOI]
(P p)
Reviews on RNases in Bacillus subtilis
Additional reviews: PubMed
Lehnik-Habrink M, Lewis RJ, Mäder U, Stülke J RNA degradation in Bacillus subtilis: an interplay of essential endo- and exoribonucleases. Mol Microbiol.: 2012, 84(6) 1005-1017. PubMed:22568516