TrmU

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  • Description: tRNA (5-methylaminomethyl-2-thiouridylate) methyltransferase

Gene name trmU
Synonyms yrrA
Essential yes PubMed
Product tRNA (5-methylaminomethyl-2-thiouridylate) methyltransferase
Function tRNA modification
MW, pI 42 kDa, 4.729
Gene length, protein length 1122 bp, 374 aa
Immediate neighbours yrrB, yrvO
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TrmU context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TrmU expression.png
























Categories containing this gene/protein

translation, essential genes, membrane proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU27500

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: mnmA/TRMU family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References