SecG

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  • Description: preprotein translocase subunit

Gene name secG
Synonyms yvaL
Essential no
Product preprotein translocase subunit
Function protein secretion
Interactions involving this protein in SubtInteract: SecG
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 7 kDa, 10.413
Gene length, protein length 228 bp, 76 aa
Immediate neighbours yvaK, yvaM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SecG context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

protein secretion, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU33630

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

Deletion of secG from the chromosome causes a temperature sensitive secretion defect. PubMed


The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: secG family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jochen Zimmer, Yunsun Nam, Tom A Rapoport
Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature: 2008, 455(7215);936-43
[PubMed:18923516] [WorldCat.org] [DOI] (I p)

Ji-Hyun Shin, Chester W Price
The SsrA-SmpB ribosome rescue system is important for growth of Bacillus subtilis at low and high temperatures.
J Bacteriol: 2007, 189(10);3729-37
[PubMed:17369301] [WorldCat.org] [DOI] (P p)

K H van Wely, J Swaving, C P Broekhuizen, M Rose, W J Quax, A J Driessen
Functional identification of the product of the Bacillus subtilis yvaL gene as a SecG homologue.
J Bacteriol: 1999, 181(6);1786-92
[PubMed:10074070] [WorldCat.org] [DOI] (P p)