BltD

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  • Description: spermidine/ spermine acetyltransferase

Gene name bltD
Synonyms bmr2D, bmtD
Essential no
Product spermidine/ spermine acetyltransferase
Function spermidine degradation
MW, pI 17 kDa, 6.087
Gene length, protein length 456 bp, 152 aa
Immediate neighbours blt, yrkA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
BltD context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

miscellaneous metabolic pathways, membrane proteins

This gene is a member of the following regulons

BltR regulon, Mta regulon

The gene

Basic information

  • Locus tag: BSU26600

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

D P Woolridge, J D Martinez, D E Stringer, E W Gerner
Characterization of a novel spermidine/spermine acetyltransferase, BltD, from Bacillus subtilis.
Biochem J: 1999, 340 ( Pt 3)(Pt 3);753-8
[PubMed:10359661] [WorldCat.org] (P p)

N N Baranova, A Danchin, A A Neyfakh
Mta, a global MerR-type regulator of the Bacillus subtilis multidrug-efflux transporters.
Mol Microbiol: 1999, 31(5);1549-59
[PubMed:10200972] [WorldCat.org] [DOI] (P p)

D P Woolridge, N Vazquez-Laslop, P N Markham, M S Chevalier, E W Gerner, A A Neyfakh
Efflux of the natural polyamine spermidine facilitated by the Bacillus subtilis multidrug transporter Blt.
J Biol Chem: 1997, 272(14);8864-6
[PubMed:9083003] [WorldCat.org] [DOI] (P p)

M Ahmed, L Lyass, P N Markham, S S Taylor, N Vázquez-Laslop, A A Neyfakh
Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated.
J Bacteriol: 1995, 177(14);3904-10
[PubMed:7608059] [WorldCat.org] [DOI] (P p)