FtsL

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  • Description: cell-division protein (septum formation), controls together with EzrA dynamics of the FtsZ ring

Gene name ftsL
Synonyms ylxB, yllD
Essential yes PubMed
Product cell-division protein
Function septum formation
Interactions involving this protein in SubtInteract: FtsL
MW, pI 12 kDa, 10.083
Gene length, protein length 351 bp, 117 aa
Immediate neighbours mraW, pbpB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
FtsL context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

cell division, essential genes, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15150

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ftsL family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: degraded by RasP, stabilized against RasP cleavage by DivIC PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: FtsL is degraded by RasP PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Gu Chen, Xu Zhang
New insights into S2P signaling cascades: regulation, variation, and conservation.
Protein Sci: 2010, 19(11);2015-30
[PubMed:20836086] [WorldCat.org] [DOI] (I p)

Original Publications

Additional references: PubMed