FatR

• Description: transcriptional repressor of the fatR-yrhJ operon
  
  

Gene name	fatR
Synonyms	yrhI, bscR
Essential	no
Product	transcriptional repressor of the fatR-yrhJ operon (TetR family)
Function	unknown
MW, pI	22 kDa, 5.621
Gene length, protein length	582 bp, 194 aa
Immediate neighbours	yrhJ, yrhH
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

electron transport/ other, lipid metabolism/ other,lipid metabolism/ other, transcription factors and their control, cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

FatR regulon, SigM regulon, SigW regulon, SigX regulon

The FatR regulon:

• fatR-yrhJ

The gene

Basic information

• Locus tag: BSU27170

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Additional information

Expression

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O08335

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • fatR-yrhJ PubMed
  • yrhH-fatR-yrhJ PubMed

• Sigma factor: SigM PubMed, SigW PubMed, SigX PubMed

• Regulation:
  • induced by unsaturated fatty acids (FatR) PubMed
  • expression is reduced in a SigV mutant PubMed

• Regulatory mechanism:
  • FatR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed