CitR

• Description: transcriptional repressor of citA
  
  

Gene name	citR
Synonyms
Essential	no
Product	transcriptional repressor (LysR family)
Function	regulation of the minor citrate synthase
Regulatory function of this protein in SubtiPathways: Central C-metabolism
MW, pI	35 kDa, 8.67
Gene length, protein length	924 bp, 308 aa
Immediate neighbours	lytE, citA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transcription factors and their control

The CitR regulon:

• citA

The gene

Basic information

• Locus tag: BSU09430

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Additional information

Expression

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: LysR family

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P39127

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: citR PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

S Jin, A L Sonenshein
Transcriptional regulation of Bacillus subtilis citrate synthase genes.
J Bacteriol: 1994, 176(15);4680-90
[PubMed:8045899] [WorldCat.org] [DOI] (P p)

S Jin, A L Sonenshein
Identification of two distinct Bacillus subtilis citrate synthase genes.
J Bacteriol: 1994, 176(15);4669-79
[PubMed:8045898] [WorldCat.org] [DOI] (P p)