QueG

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  • Description: epoxyqueuosine reductase

Gene name queG
Synonyms ygaP, yhbA
Essential no
Product epoxyqueuosine reductase
Function synthesis of queuosine, tRNA modification
MW, pI 48 kDa, 7.352
Gene length, protein length 1305 bp, 435 aa
Immediate neighbours yhzB, yhbB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YhbA context.gif
This image was kindly provided by SubtiList




Categories containing this gene/protein

translation

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU08910

Expression

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: conversion of epoxyqueuosine to queuosine PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): cobalamin, iron-sulfur cluster PubMed
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Zachary D Miles, Reid M McCarty, Gabriella Molnar, Vahe Bandarian
Discovery of epoxyqueuosine (oQ) reductase reveals parallels between halorespiration and tRNA modification.
Proc Natl Acad Sci U S A: 2011, 108(18);7368-72
[PubMed:21502530] [WorldCat.org] [DOI] (I p)